1 00:00:06,060 --> 00:00:05,250 [Music] 2 00:00:19,830 --> 00:00:06,070 [Applause] 3 00:00:22,870 --> 00:00:21,349 when i was four i told my mother i was 4 00:00:24,710 --> 00:00:22,880 going to be an astronaut so it's kind of 5 00:00:26,310 --> 00:00:24,720 being a perpetual thing from there and i 6 00:00:27,910 --> 00:00:26,320 figure if i'm going to be an astronaut i 7 00:00:29,990 --> 00:00:27,920 don't want to be getting sick 8 00:00:31,189 --> 00:00:30,000 and if someone isn't doing what i think 9 00:00:33,510 --> 00:00:31,199 about the immune system why don't i go 10 00:00:36,709 --> 00:00:33,520 look at it myself this is the mini pcr 11 00:00:39,590 --> 00:00:36,719 machine designed by mini pcr 12 00:00:42,470 --> 00:00:39,600 pcr is polymerase chain reaction 13 00:00:44,389 --> 00:00:42,480 so dna amplification we now have more 14 00:00:46,549 --> 00:00:44,399 dna amplification capabilities on the 15 00:00:48,150 --> 00:00:46,559 station but when this went up it was the 16 00:00:49,670 --> 00:00:48,160 first 17 00:00:51,590 --> 00:00:49,680 hi this is tim peake on board the 18 00:00:54,389 --> 00:00:51,600 international space station and this is 19 00:00:56,150 --> 00:00:54,399 a message to anna sophia to say a huge 20 00:00:58,470 --> 00:00:56,160 congratulations for your willing 21 00:01:00,869 --> 00:00:58,480 submission to investigate the effects of 22 00:01:02,630 --> 00:01:00,879 cosmic radiation and microgravity on the 23 00:01:04,229 --> 00:01:02,640 body's immune system so you're meant to 24 00:01:05,910 --> 00:01:04,239 have a balanced ratio of your t helper 25 00:01:07,590 --> 00:01:05,920 one and two for two cells but when 26 00:01:10,070 --> 00:01:07,600 you're in space you get a much more 27 00:01:12,149 --> 00:01:10,080 dominant t helper two phenotype which 28 00:01:14,710 --> 00:01:12,159 decreases your cell-mediated immunity 29 00:01:17,020 --> 00:01:14,720 and just generally hampers your immune 30 00:01:32,310 --> 00:01:17,030 system